بررسی نقش متادون به‌عنوان یک مخدر مناسب در عمل جراحی و پیوند عروق کرونر در معتادان به تریاک

Todays coronary artery bypass graft (CABG) is the most frequent among open heart surgeries. In our country some of people that are candidate for coronary artery bypass graft, are addict and they use opium daily, that cause multiple complication during intraoperative and postoperative periods. Inspite of several studies that methadone is used to anti-addiction therapy and for reducing the complications of opium, we decided to choose methadone as perioperative narcotic. Methadone is a long acting synthetic narcotic that we think it can be a good choice narcotic for coronary artery bypass graft. In a trial study, we choose 120 cases among the coronary artery bypass graft patients. Before induction of anesthesia, all of them received 0.6 mg/kg methadone intravenously and in the postoperative period they received 0.15 mg/kg methadone intravenously. 80.83% of this patients didn’t have pain during intraoperative and postoperative periods and we didn’t see withdrawal syndrom in intensive care unit. In 7.5% of this cases we had to use oral opium in postoperative period.